Special Talk: Nanodiamond Quantum Defects in Immunodiagnostics

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The IAVT Department, within the International College at NPUST, successfully hosted a highly technical Special Talk on Tuesday, October 14, 2025. The informative session, titled “Nanodiamonds with Nitrogen-Vacancy Quantum Defects in Immunodiagnostics,” was presented by Professor Trong Nghia Le from the National Taiwan Normal University and took place at the IAVT Department. This session provided valuable insight for students and faculty interested in the intersection of nanotechnology, quantum mechanics, and advanced diagnostics.

Professor Le began the session by providing a clear explanation of what Nanodiamonds are and exploring the fundamental principles of Nitrogen-Vacancy quantum defects, the key component that gives these tiny materials their unique sensing capabilities. He then transitioned into demonstrating the powerful applications of nanodiamonds in immunoassay, a critical field for medical diagnostics. Attendees learned how these materials, far smaller than a typical virus, can be used to dramatically improve the speed and accuracy of in-vitro testing.

The presentation featured several advanced case studies highlighting the revolutionary capabilities of this research. Specifically, Professor Le detailed the groundbreaking use of this technology in Spin-Enhanced Lateral Flow Immunoassay for High-Sensitivity Detection of Nonstructural Protein NS1 Serotypes of the Dengue Virus, illustrating how nanodiamonds achieve revolutionary sensitivity in tropical disease detection. Finally, the talk covered the innovative development of Antibody-Conjugated Nanodiamonds as Dual-Functional Immunosensors for In Vitro Diagnostics, highlighting the dual capabilities of these materials in advanced sensing technology. The session provided a fascinating look into the future of diagnostic medicine, solidifying the IAVT Department’s commitment to exploring high-impact research frontiers.